Progynova TS Patches

Progynova TS Patches are used for Hormone Replacement Therapy (HRT) for oestrogen deficiency symptoms in postmenopausal women more than 1 year postmenopause.

Prevention of osteoporosis in postmenopausal women at high risk of future fractures who are intolerant of, or contraindicated for, other medicinal products approved for the prevention of osteoporosis.

Read the Patient Information Leaflet

Like all medicines, this medicine can cause side effects, although not everybody gets them.

The following diseases have been reported more often in women using HRT compared to women not using HRT:

• breast cancer
• abnormal growth or cancer of the lining of the womb (endometrial hyperplasia or cancer)
• ovarian cancer
• blood clots in the veins of the legs or lungs (venous thromboembolism)
• heart disease
• stroke

The following is a list of side effects that have been linked to the use of Progynova TS patches:

• breakthrough bleeding at unexpected times (see also section 2 ‘HRT and cancer’)
• breast tenderness
• breast pain These side effects occur during the first few months of treatment with Progynova TS patches. They are usually temporary and normally disappear with continued treatment. If they do not, contact your doctor.

Common side effects (may affect up to 1 in 10 people):

• depression, dizziness, nervousness, lack of energy, increased sweating, hot flushes
• headache
• wind, nausea
• itching or rash at the site of application
• fluid retention, weight gain
• irregularities in your menstrual period, changes in vaginal discharge
• generalized pain Uncommon side effects (may affect up to 1 in 100 people):
• increase in blood cholesterol
• anxiety, inability to sleep, apathy, mood swings, poor concentration, extreme feelings of euphoria, tremor, agitation, altered sex drive
• pins and needles
• migraine
• visual disturbance, dry eye
• palpitations
• superficial inflammation of the veins (phlebitis), high blood pressure
• breathlessness, runny or blocked nose
• increased appetite, constipation, indigestion, diarrhoea, rectal disorder
• unusual bleeding or bruising under the skin (purpura)
• acne, hair loss, dry skin, nail problems, small skin swellings, excessive hair growth
• joint pain, muscle cramps
• increased and frequent urge to pass urine, urinary incontinence, bladder infections (cystitis), discoloured urine, blood in the urine • benign growths in the lining of the womb, thickening of the lining of the womb, problems with the womb, swollen breasts, tender breasts v022_0 Page 10 of 11
• tiredness, irregular blood tests, high temperature, lack of energy, feeling generally unwell Additional side effects reported by healthcare professionals:
• reduced oxygen flow to the brain or to a section of the brain (see Section 2 ‘Stroke’)
• abdominal pain, bloating, yellowing of the skin or eyes (jaundice)
• exacerbation of hereditary angioedema (swelling of face, tongue and/or throat and/or difficulty swallowing, hives, breathing difficulties)
• contact dermatitis
• fibroids The following side effects have been reported with other HRTs:
• gall bladder disease
• a variety of skin disorders: o discoloration of the skin especially of the face and neck known as “Pregnancy patches” (chloasma) o painful reddish skin nodules (erythema nodosum) o rash with target-shaped reddening or sores (erythema multiforme

This is only a summary, please refer to patient information leaflet provided or link below for comprehensive list. Patient Information Leaflet

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